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Earlier this month, state media noted a senior government advisory body - the China Council of International Cooperation on Environment, made up of international experts - was recommending a target of 4-54-5%ductions a year until 2050.
This may explain why guidelines have evolved during the past decade, recommending a target of 10 to12 g/dl for the latest KDOQI guidelines [ 16, 17], which is narrower for ERBP (11 12 g/dl) [ 18], and much higher than the new KDIGO (9.5-11.5 g/dl) [ 6].
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Identifying early changes in specific zones of the symptomatic joints can aid clinicians tremendously in recommending a targeted joint preservation approach versus focal or compartmental joint replacements.
The NKF KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease recommend a target protein intake of 0.8 g/kg body weight per day (the recommended daily allowance) for nondialysis-dependent DKD (Grade B evidence) (4).
See related research by Spahn et al., http://ccforum.com/content/17/2/R76 In the latest recommendations for the management of bleeding following major trauma, Spahn and colleagues recommend a target haemoglobin of 7 to 9 g/dl to initiate blood transfusion [ 1].
Here Suicide Prevention Australia has recommended a target of 50% reduction in suicide deaths in 10 years, as an aspirational statement to galvanise support and action.
New guidelines recommend a target glycated hemoglobin (HbA1c) of 7.5% to 8.0% in elderly persons with type 2 diabetes mellitus (T2DM), but real-world data regarding outcomes associated with different HbA1c levels in the elderly are limited.
Accordingly, Brain Trauma Foundation recommends a target CPP between 50 and 70 mmHg [48].
European [9] and Canadian [10] guidelines concur and both recommend a target of 20 25 kcal/kg/day.
The guidelines for treatment of hypertension in patients with CKD recommend a target BP <130/80 mm Hg, with no clear threshold on the lower limit.
The Surviving Sepsis Campaign recommends a target mean arterial pressure (MAP) of at least 65 mmHg; however, it is unclear whether this target is more or less effective than a higher target MAP.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com