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Physicians disagree with some recommendations of the protocol and believe their clinical judgment should supersede the recommendation in certain circumstances.
Based on the teleconsultation, in 17 out of 96 cases (18%) physicians considered the problem to be less urgent than the recommendations of the protocol.
Some of the physicians and nurses are not aware that there is a protocol for asthma management, others are not familiar with the recommendations of the protocol and they did not think it is different from their practice.
By reproducing their methodology as far as possible (e.g. exclusion of specific taxa, weighting of specific source trees, use of standard rooted MRP coding), except where these conflict with the recommendations of the protocol, we aim to assess the specific impact of the protocol on the overall supertree topology.
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To ensure that the self-interested consumers will take the recommended scheduling actions, a punishment phase is incorporated in the recommendation of the protocol designer upon observing deviations.
Total RNA was extracted from tissue specimens using the RNeasy Kit (Qiagen, Tokyo, Japan) according to the recommendations of the manufacturers protocol.
Although severe hypertension and hypertensive crisis were common, IV antihypertensive treatment was often not installed, against the recommendations of the hospital protocol.
The recommendations of these protocols are generally based on previous glucose levels and insulin dosing according to a 'sliding scale' protocol (a predetermined amount of insulin is administered according to the actual BG) or 'dynamic' protocol (the dosage of insulin is changed by a certain amount, according to the actual BG) [ 15].
On recommendation of the SMC, the protocol was later amended to explore a fourth dose, 12 mg kg 1, in patients with high (⩾50 mg l 1) baseline serum CRP at one centre only.
3 Education and several practical recommendations for successful implementation of the protocol were offered to hospitals.
All animal procedures were conducted in accordance with the recommendations of the Canadian Council on Animal Care, under a protocol approved by the University of Western Ontario Council on Animal Care.
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