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Recommendations for validation studies of new cardiac output monitors 1.
The new TaqMan probe based real time PCR assays were validated according to "minimum information for publication of quantitative real time PCR experiments" (MIQE) guidelines for the publication of quantitative real time PCR experiments suggested by Bustin et al. (2009), also considering the OIE recommendations for validation of PCR methods used for the diagnosis of infectious disease [ 28, 33].
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Recommendations for further validation experiments and improvement of the interlaboratory results obtained are given.
Therefore, apart from summarizing the role of flow cytometry technology in various stages of drug development, this manuscript focuses on recommendations for the validation of methods applying flow cytometry.
To address this unmet need, the Association of Molecular Pathology, with organizational representation from the College of American Pathologists and the American Medical Informatics Association, has developed a set of 17 best practice consensus recommendations for the validation of clinical NGS bioinformatics pipelines.
In this short review, the research gaps and recommendations for the validation of integrated and sociotechnical intervention approaches that are more likely to improve farmers' engagement and technology adoption in Africa are discussed.
Recommendations for standardisation, validation and reproducibility are summarised in Box 8. MRI methods for use with antivascular and antiangiogenic drugs are still in their infancy, and rapid progress is likely in the next few years.
This should entail adherence to NCI-EORTC recommendations for biomarker validation [ 45], requiring the incorporation of stringent quality control procedures, accurate quantification and scoring methods and unbiased thresholding of expression values.
This paper explores the merits and shortcomings of each of these design approaches, and provides recommendations for fatigue-life validation of endovascular implants.
Two case studies are presented in which quality control samples and standards meet all acceptance criteria (based on Standard Operating Procedures and the Food and Drug Administration's recommendations for bioanalytical method validation) but failed the proposed system suitability test, and thus were rejected.
Plasma cortisol was measured by radioimmunoassay (Coat-A-Count Cortisol: Diagnostic Products Corporation, Los Angeles, CA, USA) used according to the manufacturer's recommendations and validation for porcine plasma [ 11].
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