We consider a two-stage process, where the acquired information from Stage I (with a small sample size (m)) would be utilized for sample size (n) recommendation for Stage II study aiming for a more accurate estimation.
Although chemotherapy is not a routine recommendation for stage II colon cancer by the U.S. national guidelines, 20-30% of patients have received chemotherapy.
Current treatment recommendations for advanced stage prostate disease are based on clinical trials that include conventionally-fractionated radiation therapy and long-term ADT [ 39- 41].
Oncologists involved in the clinical management of breast cancer have to consider several different clinical and molecular characteristics of the tumor, in addition to patient preferences and comorbidities, when formulating therapeutic recommendations for early stage, potentially curable cancers.
The same therapeutic recommendation is for stage III, when the tumor invades through the airway perichondrium and to the cartilage or to the muscle deeply, but not into the submucosa.
In this resource-adapted consensus, we summarise recommendations for diagnosis, staging, risk stratification, and treatment of common B-cell non-Hodgkin lymphomas in Asia.
In 2007, the International Society for Cutaneous Lymphomas ISCLL) published their consensus recommendations for the staging of MF and SS and later validated independently.
Current recommendations for local staging of rectal cancer consider performing endorectal ultrasonography or MRI, combined with CT of the chest, abdomen and pelvis in search of distant metastases.
Comparison of recommendations for advanced stages of breast cancer has not been performed since there was only one guideline that included it [ 6].
These varying recommendations for imaging staging for occult metastases in women with newly diagnosed breast cancer reflect the paucity of evidence on this issue in the setting of early stage disease without symptoms suggestive of metastases.
