It has already been established that dishonest recommendations are difficult to detect when either the percentage of the dishonest recommenders is high or the MO level is very low.
Finally, recommendations are difficult to make based on the research.
The evaluation conducted here shows parallels to prior studies in that general conclusions or recommendations are difficult to distill.
The generality of our recommendations is difficult to predict, but they are likely to apply in comparable, developed countries with low prevalence of head lice such as the Nordic countries.
International comparisons of risk-appropriate screening in accordance with guideline recommendations are difficult to ascertain, given that healthcare authorities' endorsement of screening modality and timing of repeat testing vary across countries [ 18, 33, 34].
Furthermore, the included studies were distinctly different in design with diverse populations of patients, choices of antibiotics, durations of prophylaxis, and a heterogeneous observation period after removal of the catheter so that standardized recommendations are difficult to make.
Furthermore, in clinical practice, most of these recommendations are difficult to transfer into the "wide-spectrum" of phenotypes particularly in the case of patients first diagnosed in adult life.
In Europe and the US, the regulatory authorities recommend that SSRIs should only be used when the benefits outweigh the risks, but such recommendations are difficult to follow when the risks are not fully known.
However, these recommendations are difficult to implement because this is a complex intervention that is time consuming for physicians and supposes a high level of understanding and adherence by the patient.
This is time-consuming and strenuous, and hence personalized prior knowledge recommendation is difficult to perform.
