P6-mediated inflammatory cytokine secretion is therefore dependent on the presence of a lipid motif on P6 and the ability of APC to recognize this motif via TLR2.
A highly specific tool capable of recognizing Myc via pThr58 is needed to monitor activation and localization.
Importantly, WDR5 also binds to H3 itself [ 16, 23], recognizing Arg via the same binding pocket in which the MLL WIN peptides bind [ 21, 22].
Linking and de-linking games can occur by recognizing complementary markets, via special clauses in contracts, or by influencing the perceptions of other players.
Microglia are involved in the initial immune response against PM by recognizing bacterial components via the toll-like receptors 2 and 4 subsequently releasing inflammatory mediators [45], [93].
MacRae and colleagues find report that a network of water molecules in the t1A pocket provides the specificity for recognizing adenine, especially via its N6 amine.
However, a direct evidence of Eps15 as an adaptor protein recognizing ubiquitinated EGFR via interactions with EGFR-attached ubiquitin has so far not been presented.
Hence these proteins are likely to function independently of any modification, probably by directly recognizing invading DNA via their C-terminal wHTH domains.
In addition, for NCU07846 the zinc-finger is the only annotated DNA-binding domain in this protein (Fig. 2a), suggesting that it recognizes TTAGGG repeats via this domain.
This effector is recognized via the TIR-NB-LRR resistance (R) protein RPS4, which triggers the HR via an EDS1/PAD4 dependent pathway which is also required for cell death in the acd11 mutant.
The usual explanation for this effect is that real words are recognized quickly via their global features, and their constituents (the letters) can be inferred quickly, whereas nonwords, being novel stimuli, require sequential letter-by-letter processing.
