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MDA-5 recognizes longer RNAs (>1 kb) that are encoded by positive-stranded viruses such as the picornavirus encephalomyocarditis virus [85].
We therefore examined chondrocytes from OA and non- or early OA patients for the presence of dsRNA intermediates with an antibody that specifically recognizes longer stretches of dsRNA.
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Mafs unique DNA-binding domain contains a highly conserved extended homology region (EHR) that allows to recognize longer DNA sequences than other basic leucine zipper (bZIP) transcription factors.
Although the effect of adding the error predicted by an ANN reduced with lead time, probably due to the difficulty in recognizing longer patterns by neural networks, the predictions were fairly good till five time steps ahead.
While the site does allow for some Boolean searches (those directed by qualifiers such as "and", "or" and "not") to narrow search results, some users complain that it does not recognize longer search strings.
GacH was recently shown to recognize longer acarbose homologues but exhibits only low affinity to acarbose [ 68].
It has been speculated that a number of ZFDs in tandem recognize longer DNA sequences (Alwin et al., 2005; Beerli and Barbas, 2002; Beerli et al., 2000; Kim and Pabo, 1998; Liu et al., 1997; Pabo et al., 2001).
Similar in concept to TALEs, eukaryotic zinc fingers (ZFs) are small (∼30 amino acid) modular domains that bind to 3 bp DNA regions with engineerable sequence specificity and can be linked into multifinger arrays that recognize longer sequences.
Taken together with the aforementioned multiplicity of ZFDs in chimeras, these findings suggest that chimeric zinc finger transcription activators and zinc finger transcription repressors potentially recognize longer DNA sequences.
It is generally recognized that longer and thinner ducts are beneficial to reduce shunt current but detrimental to minimize pumping power.
The un-melted particles can be clearly recognized at longer spray distances and the porosities of the coatings are increased by increasing the stand-off distance.
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