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Their primary function was initially thought to be the direct inhibition of translation, but they are now recognized to target mRNAs for degradation [ 42].
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Along with its recognized ability to target rapid decay of an array of inflammatory mediators, the ARE-binding protein TTP has been shown to inhibit expression of a wide range of cancer-associated factors [ 25, 38- 44].
Although previously viewed as relatively inert structural proteins, histones are now recognized to be the targets of multiple dynamic posttranslational modifications, particularly on their C-terminal tails.
In contrast, considerably less is known about how bacterial sRNAs are recognized to interact with their targets.
For these reasons, ADA_BOVIN is widely recognized to be a very complicated target for computational studies.
Increasing levels of PA and reducing sedentary time (ST) are recognized as factors to target in an effort to curb chronic disease morbidity and mortality.
Recognizing faces corresponding to target individuals remains a challenging problem in video surveillance.
Zinc finger motifs are thought to recognize and bind to target DNA sequences, but they are not required for transcriptional activity [ 49, 50].
In some cases, it is thought that TE may mediate the function of lncRNAs, allowing them to recognize and bind to target mRNAs containing TEs [ 37].
These surface-bound ligands recognize and bind specifically to target cells.
The first widely recognized treat-to-target trial was conducted by Riddle et al. 6.
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