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IL-15, a recognized potent positive modulator of NKG2D-dependent responses of NK cells is rendered poorly activating in the presence of Tex [65].
Alternatively, histones are recognized potent platelet stimuli and can associate with platelets directly (Fuchs et al, 2011).
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These receptors are the cell's way of recognizing potent hormones like estrogen, retinoic acid and thyroid hormone.
In addition to their physical applications, phenothiazine derivatives have been recognized as potent anti-psychotic [20], anti-infective [21], antioxidant, anti-cancer [22] and anti-Parkinson agents [23].
Nannochloropsis gaditana is a microalga characterized by its high lipid content and as an important source of carotenoids, recognized as potent natural antioxidants.
Both SS and Fas activation are recognized as potent inducers of endogenous ceramide.
Plant secondary metabolites, particularly polyphenols, are also increasingly recognized as potent antimicrobials [ 11].
IgG autoantibodies and immune complexes have long been recognized as potent pathologic triggers of inflammatory responses.
Independent of their antibiotic properties, doxycycline and other members of the tetracycline family of antibiotics have been recognized as potent anti-inflammatory and immunomodulating agents [ 28– 31].
For over 10 years, DNAJ (HSP40) chaperones have been recognized as potent modifiers of polyglutamine aggregation and toxicity (Muchowski and Wacker, 2005).
The ELR + family of CXC-chemokines to which interleukin (IL -8 belongs are recognIL -8as potent promoters of angiogenesis belongsue of the Glu-Leu-are (ELrecognizedmmediasely potenting their first N-terminal cysteine residue [ 11].
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