Complex 1 cleaves pBR322 DNA via hydrolytic pathway and recognizes minor groove of DNA double helix.
These results suggest that the VHHs antibody fragments might recognize minor antigenic differences between natural TcTSs resulting in different inhibition levels.
The results obtained in this work, showing that different recombinant TcTS protein products are inhibited to different extents by the four VHHs tested, indicate that VHHs could recognize minor antigenic differences present in the polymorphic population of natural trans-sialidases, as this enzymatic activity potentially derives from the simultaneous expression of about 70 different genes [39].
The therapeutic efficacy is based on donor-derived CD8+ T cells that recognize minor histocompatibility antigens (MiHAs) expressed by patient's tumor cells.
Although daily monitoring was facilitated by the fact that only 2 macaques remained and that the caretakers were more experienced to recognize minor changes in behavior, symptoms were first detected 1,340 and 1,398 days postinfection, respectively.
In contrast to the artificial log-normally distributed data, pooled subpopulation means are not sensitive enough to recognize minor, but significant differences between case and control for arsenic for FC ≤1.5 (Table 2).
The Latin church had long recognized four minor orders (porter, lector, exorcist, acolyte) and four major orders (subdeacon, deacon, priest, bishop).
In the present study, PC2 and PC3 recognized two minor depositional processes (channel-lag deposits and muddy deposits resulting from episodic flooding).
However, it has long been recognized that minor impairment of the renin angiotensin aldosterone axis is seen in some patients at the time of presentation.
Indeed, although nectar is composed primarily of sugars, it has now been recognized that minor nectar constituents, such as secondary metabolites, can be crucial in mediating plant interactions with other species (Adler and Irwin 2012).
