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White adipose tissue (WAT) fibrosis – the buildup of extracellular matrix (ECM) proteins, primarily collagen – is now a recognized hallmark of tissue dysfunction and is increased with obesity and lipodystrophy.
The cleidoic avian egg is a highly ordered structure and the recognized hallmark of reproduction in birds.
Furthermore, enhanced activation of Akt is a recognized hallmark of increased insulin action (Whiteman et al, 2002).
The recognized hallmark of RA pathogenesis is the involvement of immune cells which produce many mediators potentiating an inflammatory environment.
Remodeling of energy metabolism is a recognized hallmark of cellular transformation that supports the sustained proliferation of cancer cells under conditions that restrict normal cell growth.
In addition, it should be noted that our results apply to the pandemic scenario where a shift in the age distribution toward greater morbidity and mortality in younger age groups is a recognized hallmark compared to seasonal influenza [ 14].
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With an expanded view of tumor complexity we identify those elements key to effective cryoablation and strategies designed to optimize cancer cell mortality with a consideration of the now recognized hallmarks of cancer.
The exclamation quickly became a popular catchphrase, while the running gag of Kenny's recurring deaths are one of the more recognized hallmarks among viewers of modern television.
The genomic instability observed in tumor cells and all other recognized hallmarks of cancer are considered downstream epiphenomena of the initial disturbance of cellular energy metabolism.
However, persistent RTG activation leads to eventual nuclear genomic instability and other recognized hallmarks of cancer (Butow and Avadhani, 2004; Singh et al., 2005; Seyfried and Shelton, 2010).
Elevated levels of tau and phoshorylated tau are recognized hallmarks in the CSF supported diagnosis of Alzheimer's disease (Kapaki et al., 2007; Snider et al., 2009; Hertze et al., 2010; Scheurich et al. 2010; van Harten et al., 2011).
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CEO of Professional Science Editing for Scientists @ prosciediting.com