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In the case of HLA-SE, it is hypothesized that cigarette smoking leads to inflammation and citrullination of certain peptides, which – when presented within the context of HLA-DR4 molecules – are specifically recognized, contributing to anti-citrulline autoimmunity [ 37].
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Obesity is a recognized contributing factor to urinary incontinence in older women and men (45).
Three factors may be recognized as contributing to the character of Mesopotamian art and architecture.
Inflammation in the nervous system is widely recognized as contributing to a number of neurological conditions.
Spate irrigation is increasingly recognized as contributing to potential of accessible water-resource use, local food production, and resource sustainability.
A number of risk factors have been recognized as contributing to the disease, including obesity, coronary artery disease (CAD), hypertension, hyperlipidemia, diabetes, smoking, and family history of premature CAD.
Copy number variation (CNV) in the germ line is increasingly recognized as contributing to developmental defects and susceptibility to diseases including cancer, similar to single nucleotide polymorphisms (SNP) [3], [4].
B lymphocytes are recognized as contributing to anticancer immune responses via their secretion of antigen-specific immunoglobulins.
The IVF treatment process itself is increasingly recognized as contributing to the physical, psychological and emotional burden on infertility patients (Boivin and Takefman, 1996; Cousineau and Domar, 2007).
Fusion transcripts are common in haematological malignancies and they are also recognized as contributing to the pathogenesis of solid tumors [ 20].
Bacteriophage insertions have previously been recognized as contributing to macromolecular genetic diversity between related outbreak-associated L. monocytogenes strains [ 12, 36].
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