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The conditions that need to be satisfied for a TF to recognize and bind a specific DNA sequence within a promoter region are mimicked by the sequence-matching rule between the sequences associated with the respective TFs and PRs.
A B cell becomes activated when its receptor recognizes an antigen and binds to it.
When the C-SH2 domain recognizes a bipartite pTyr ligand it binds one pTyr, and the N-SH2 domain binds the other pTyr, reversing the autoinhibition of the phosphatase.
The ELISA method uses antibodies linked to a reporter enzyme to specifically recognize and bind a target compound in a mixture of compounds.
This led us to hypothesize that the 2E12 antibody might recognize a bovine serum component specifically bound to late apoptotic cells.
Accordingly, a consensus sequence motif can be recognized to bind to the ANKRA2 and RFXANK ANK repeats.
Hypermutation allows for the selection of B cells that express immunoglobulin receptors possessing an enhanced ability to recognize and bind a specific foreign antigen [ 5]. (7) The receptors of the lymphocytes are created somatically, which means immune cells can manufacture their receptors epigenetically from genetic raw material [ 5].
An additional characteristic of the genes encoding class I receptors is a high level of polymorphism, which enables the host to recognize and bind a wide array of foreign peptides [4].
Damaged proteins are often recognized and bind to Hsp40, which in turn recruit Hsc70.
This module was initially recognized to bind tyrosine-phosphorylated (pTyr) NPXY motifs [15].
Nitroimidazoles are recognized to bind selectively to hypoxic cells [ 23] and are reduced intracellular.
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