Indeed, a cohort of poly- and monoclonal antibodies that recognize site-specificic acetylation marks with improved selectivity have been raised, and many are commercially available.
All enzymes that recognize sites beyond the amplification junction leave the amplicon-specific ApaLI fragment intact (Pop4 210 clone1, Figure 2D).
Conversely, the fruit fly nuclear receptor knirps-like (knrl) and the Pax protein Poxn do not have direct human orthologs, and recognize sites not bound by human TFs.
Mature miRNAs recognize sites in the 3′-untranslated regions (UTR) of the target mRNAs and cause mRNA degradation or translational repression.
We hypothesized that CLEC12A could also recognize sites of membrane damage triggered by vacuolar disruption after bacterial entry (Tattoli et al., 2012; Thurston et al., 2012).
MicroRNAs (miRNAs) are small non-coding RNAs that recognize sites of complementarity of target messenger RNAs, resulting in transcriptional regulation and translational repression of target genes.
How do histone demethylases recognize sites of DNA damage and how do they contribute to DNA repair at the molecular level?
Moreover, H3K4me3 and DNA hypermethylation are mutually exclusive: DNMTs only recognize sites with unmethylated H3K4 and loss or gain of H3K4 methylation is a strong predictor of promoter DNA methylation status.
