The contribution of foam-like MGCs to synovitis in OA and RA deserves further study, given recognized associations between human arthritis, obesity and metabolic syndrome [ 50], and preclinical evidence that synovial foam-like MGCs might be associated with increased bone resorption [ 51].
Despite the recognized association between mood disorders and ED, few studies described the relationship with BD and its broader definition of bipolar spectrum (BS).
There is a well recognized association between depression and diabetes.
The widely recognized association between NAFLD and insulin resistance suggests a role of the insulin signaling pathway in hepatic steatosis.
In fact, there is a recognized association between endometriosis and clear cell, low-grade serous, and endometrioid ovarian cancer [ 25].
In addition, there is a recognized association between fetal macrosomia and long-term consequences for the newborn, including obesity, diabetes, and heart disease [ 7– 20].
There is a recognized association between pulmonary infection with rapid growing mycobacteria [ 9, 10] (M. abscessus and M. fortuitum) and esophageal disorders.
Despite the recognized association between GBA mutations and PD, it is unknown how heterozygous GBA mutations affect GCase activity in PD brains.
However, given the recognized association between retinopathy and age, this may be expected to bias the results toward a higher prevalence of retinopathy recently, rather than the reduction that we observed (2).
Although statins have a good safety profile, given the recognized association between statin use and hepatic and muscle dysfunction [ 17, 18], both well-recognized features of dengue, our primary objective was to assess the safety of lovastatin in dengue patients.
In spite of this recognized association between elevated cobalt and chromium levels in blood and malfunctioning implants, there is limited information about the range of acceptable metal ion concentrations and where toxicity is introduced.
