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In order to rationalize the molecular basis of the DNA G-quadruplex versus duplex recognition preference, docking and molecular dynamics studies have been performed.
This recognition preference suggests that distal sequences flanking the K9/K27 consensus "ARKS" motif contribute to H3K27me3 recognition.
This difference may result from the recognition preference of the mAb for un- or under-glycosylated MUC1 tandem repeats.
As a result, panels b and c of Fig. 9 display a recognition preference of the central portion of the 4044 amino acid sequence.
The duration of exploration of each goal box (when the mouse is sniffing the grid delimiting the goal box) was measured, and the percentage of time the mouse took to explore the congener was used as an index of social preference (recognition preference).
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Phage display frequently identified recognition preferences for amino acids different from those present in the original crystal structure.
As a test set, we use a considerable amount of recent phage display data that describe the peptide recognition preferences for 169 naturally occurring and engineered PDZ domains.
In recent years, the development of large-scale technologies has enabled exhaustive studies on the peptide recognition preferences for a number of peptide-binding domain families.
The sequence specificities of RNA-binding proteins display deep evolutionary conservation, and the recognition preferences for a large fraction of metazoan RNA-binding proteins can thus be inferred from their RNA-binding domain sequence.
When human influenza viruses and avian influenza viruses infect the same intermediate host, gene re-arrangement between the human and avian influenza viruses is likely to occur, enabling the viruses to alter their recognition preferences of sialic acid on surface glycoprotein (Dawood et al. 2009).
Importantly, this feature appears to have coevolved coordinately with the size recognition preferences of the chaperone complement present in each particular organism [21].
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