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The selected examples are discussed taking into account the anion binding mode, the association strength, the selectivity, and the structural features of the recognition phenomena.
In this context carbohydrates are ideal tools, not only because they are involved in a variety of recognition phenomena of biological relevance, but also because they are ideal scaffolds to generate libraries of bioactive compounds.
To gain some insight on the dynamic aspects of recognition phenomena, we conducted molecular dynamics simulations of the aminoglycoside paromomycin bound to a eubacterial ribosomal decoding A-site oligonucleotide.
DNA sequence specificity plays a critical role in a number of biological processes, and influences a diverse range of molecular recognition phenomena, including protein DNA, oligomer DNA, and ligand DNA interactions.
This provided detailed information on relevant properties of the investigated host-guest structures and showed that the active unit of SNeuAC-C14, i.e. its spiro tricyclic moiety, was located in the polar head region of the liposome bilayer, which is an important requirement for recognition phenomena.
Results from 25 ns of simulation time revealed that: (i) the neamine part of the antibiotic represents the main anchor for binding, (ii) additional sugar rings provide limited and fragile contacts, (iii) long-resident water molecules present at the drug/RNA interface are involved in the recognition phenomena.
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The exploitation of molecular recognition phenomenon is no longer limited to affinity chromatography modes.
Theoretically predicted hydrogen bonding interactions revealed a favorable chiral recognition between the receptor and l-mandelic acid, which is well correlated with experimentally observed enantioselective recognition phenomenon.
A number of researchers however have championed an alternate idea: that these crests were used for some form of "species recognition" phenomenon: that they evolved primarily to help individuals correctly identify members of their own species, and separate out those of other species, either to make sure they mate with the right ones, or keep track of their herd or similar.
BeWo adhesion-selected Tz745 and Tz748 also show the characteristic parity-dependent serological recognition phenomenon [54].
Fungi display a non-self recognition phenomenon termed heterokaryon incompatibility that operates when cells of unlike genotype fuse and leads to the cell death of the fusion cell.
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