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The first step in the majority of nuclear import/export pathways is the recognition of targeting signals by soluble transport receptors (Karyopherins, or Kaps).
In yeast, several receptors (Tom70, Tom20 and Tom22) mediate the recognition of targeting sequences or internal information in the proteins being imported [34].
Since the last amino acid residues of helix 8 are dispensable for rhodopsin folding and function, we propose that this domain participates in the recognition of targeting factors involved in transport to the rhabdomeres.
Although the autophagosomes seem to form and fuse to the lysosomes efficiently, there is a failure in the recognition of targeting signals, such as p62 or polyubiquitin, that results in delayed engulfment of cytosolic macromolecules and damaged organelles.
There is a mechanistic difference between recognition of targeting signals by preprotein receptor proteins in plastids and mitochondria, the former involving a GTP/GDP cycle while no energy requirement is observed for receptor binding in mitochondria.
MIPNPs showed selective recognition of target bacteria as detected by flow cytometry.
The guide RNA in the CRISPR-Cas immune/editing system is poised to initiate recognition of target DNA.
This format of detection shows more sensitivity and specificity for recognition of target nucleic acid compared with homogenous format [38].
As a result, the specific recognition of target and fluorescent signals are accumulated through the process in short 1 h.
This review also describes molecular imprinting techniques to fabricate hydrogels for specific molecular recognition of target analytes.
(A) MiRNAs guide the recognition of target mRNAs through imperfect matches with their targeting sites and thus regulate the expression of target mRNAs at the post-transcriptional level.
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