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This purpose is quite different, and requires that outcomes are formally recorded, in a standard manner, and it is for this purpose that recognised outcome measures are mandatory.
All included trials used internationally recognised outcome measures to evaluate cognitive function, including the MMSE, MoCA, MBI and WMS.
Instead they called for evidence that outcomes were recorded against recognised outcome measures.
Neither centre apparently attached great importance to this: Lisbon made some use of recognised outcome measures in two thirds (68%%) of cases, Essen not in any.
However, recognised outcome measures are not needed for either of these purposes: any system that has meaning to its users may be sufficient, including simple but careful recordings of symptoms in patients' notes.
Most studies used study-specific questionnaires with only a few using a recognised outcome measure.
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Treatment includes rest, splintage and surgery with each modality having specific indications and recognised outcomes.
It is increasingly recognised that outcomes for patients with cancer are determined by host as well as tumour-related factors.
A number of newer licensed biologic agents are also effective in improving recognised disease outcomes for joint disease and/or co-morbidities, although the range of clinical benefits seen thus far with anti-TNF drugs will be hard to match or exceed.
The EU condemned the referendum as illegal and said it would not recognise the outcome.
The EU said it would not recognise the outcome of the referendum.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com