Importantly, the majority of co-regulated genes were reciprocally regulated by CepR and CciR.
Among the reciprocally regulated genes we found 34 genes up-regulated in Th1 condition and only six genes behaved in the opposite manner.
CciR reciprocally regulated many genes previously reported to be CepR-regulated [ 27, 28] (Tables 1 & 3).
Our study now shows that presence of CciIR in certain B. cenocepacia strains has major implications for QS-regulated genes across the genome; most notably genes reciprocally regulated by CepIR and CciIR.
More than one quarter of the unique ORFs that were reciprocally regulated by CepR and CciR showed the same trend in regulation in the cepR and cepRcciIR mutants.
Open image in new window Figure 4 M IL-23), M IL-23M1 polandzations are reciprocally regulated.
Glucose can also be synthesized through gluconeogenesis, a process reciprocally regulated compared to glycolysis in order to keep the metabolism of the cell efficient (Berg JM, 2002).
In this review, we will discuss how the PPP is regulated and how the PPP and glycolysis, another important glucose metabolic pathway, are reciprocally regulated and balanced in the context of nutrient uptake and certain stress responses in cancer.
Thus, c-Met activation is reciprocally regulated by phosphorylation between c-Met serine and tyrosine residues through PP2A induction in the presence or absence of mutant SOD1 expression, and HGF functions more efficiently in ALS and ALS-related diseases.
This result suggests that, first, foxi3a is genetically upstream of foxi3b and, second, foxi3a and foxi3b can be reciprocally regulated by a positive feedback loop.
The guanine nucleotide binding state of Rho1 is reciprocally regulated by its guanine nucleotide exchange factors (GEF) and GTPase activating proteins (GAP) [4].
