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The reciprocal conversion is neglected.
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Also, two variant α-globin gene alleles consisting of a small DNA segment from the other α-globin gene paralogue (α212 and α121) are most likely the result of a single crossover between a normal and a recombinant allele, although a non-reciprocal gene conversion event cannot be completely ruled out [ 23].
Earlier studies of MHC class I nucleotide sequences in mice have proposed that regions with high levels of CpG dinucleotides are involved in non-reciprocal recombination (gene conversion) [ 31].
We have developed an experimental system to assay conversion and reciprocal exchange between tandem repeats in Drosophila melanogaster.
The close relationship between CEACAM1 and its ITAM-encoding relatives appears to be maintained by gene conversion and reciprocal recombination.
The global test for reciprocal recombination or gene conversion events was performed with 10,000 permutations of the sequence alignment to assess significance.
Although possible recombinant alleles were removed from the analyses of the present study by Satta's method (Satta 1992), we further investigated for reciprocal recombination or gene conversion using the GENECONV program (Sawyer 1989) to dismiss the possibility that recombination caused KB(m) deceleration.
Ectopic pairing between homoeologous chromosomes could lead to reciprocal exchanges and gene conversions (Gaeta and Pires, 2010, Soltis and Soltis, 1999).
We assume that non-HEase induced gene conversion is globally reciprocal and hence negligible.
Gene conversion, a non-reciprocal recombination process commonly affecting Alus, has also operated in the AluYi6 subfamily.
This makes it likely that these additional two mutations are shared due to retrotransposition rather than parallel mutation or gene conversion, a non-reciprocal recombination process that affects Alu elements, so there may be two active source genes in this small subfamily.
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