Exact(1)
Some important variables, such as recipient panel reactive antibodies, were not recorded.
Similar(58)
Schematic diagram of the experimental design for re-introduction of miR-142−/− BM into lethally irradiated WT mouse recipient (left panel), which results in reduced platelet counts relative to controls, 6 weeks after transfer (right panel).
The best newcomer is awarded £5,000, as is the recipient of the panel prize.
Hemipelvic allograft selection was tested in 10 virtual recipients with a panel of 10 potential allografts, including one from the recipient himself (trap graft).
Having shown a significant association of a drop in CMV specific CD4 T cells with an increase in viremia as compared to a considerable stability of CMV specific CD8 T-cell levels, the respective relationship of CMV specific CD8 T cells with viral replication was analyzed in a subpopulation of 15 transplant recipients with a panel of five CMV peptide-bound MHC class I pentamers.
In that study, 4 observers performed allograft selection for 10 virtual recipients from a panel of 9 real allografts and 1 trap graft.
Such situations could include the presence of a nondiabetic HLA-identical sibling, a recipient with high panel-reactive antibody levels, or associated morbidities that predict a high risk of mortality while the recipient is on the waiting list.
In contrast, in 60% of the cases, transplanted epithelium from mutant donors failed to grow out and only rudimentary ductal trees were detected in the recipients, mutant, left panel).
Such circumstances may arise in the presence of an HLA-identical sibling or a recipient with high panel-reactive antibody levels, which would make tissue matching very difficult, or associated morbidities that predict a high risk of recipient mortality while on the waiting list.
The recipient had Class I panel reactive antibodies' (PRAs) titre of 97%, but T- and B-cell IgG flow cytometric crossmatch was negative.
High-level multilineage engraftment of blood, BM, spleen, lymph nodes and thymus was found in the recipients receiving CD41intCD61int cells (supplementary material Fig. S1, top panel) and secondary recipients were successfully engrafted with BM from these primary recipients, thus demonstrating that the CD41intCD61int population contains bona fide HSCs (supplementary material Fig. S1, bottom panel).
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