Sentence examples for recipient lymphocytes from inspiring English sources

If neither donor nor recipient lymphocytes are affected, then donor and recipient lack antigens in common.

For alloactivation, mixed lymphocytes culture reaction was performed using donor cells which were inactivated and incubated with equal cell number of recipient lymphocytes (200.000 total cells/well) for 72 h at 5% CO2, at 37°C.

Even though 2-MHC-haplotype-matched animals have identical genetics in the MHC loci, polymorphisms at other genetic loci can be used successfully to differentiate donor and recipient lymphocytes.

Finally, in our study and others, some gene expression differences attributed to ACR in heart tissue may reflect the detection of strain-associated gene expression attributable to recipient lymphocytes that have infiltrated the donor allograft.

The aim of this study was to investigate effect of suppression of donor KC B7 expression on recipient lymphocyte activation and secretion of interleukin-2 (IL-2) in vitro.

Ross et al. have investigated trogocytosis in both the allogeneic experimental setting and in patients with multiple myeloma and other B-cell malignancies; they identified 2 molecules as potential transfer candidates, human leukocyte antigen (HLA -G and tHLA -Gmolecule CD86, and identheied T cells as the most common recipient lymphocyte suB7opulation [ 8].

Intragraft expression of costimulatory molecules (B7.1, B7.2), cytokines (IL-2, IL-4, mIL-10, IFN-γ), and iNOS molecules were markedly lower in tolerant grafts that survived for >100 days; recipient T lymphocytes demonstrated hyporeactivity to donor and third-party antigens in mixed lymphocyte cultures.

Kinetic analysis of aortic allograft rejection corroborated our previous observations [9], [11]: infiltration of the adventitia by recipient's lymphocytes began 5 days post transplantation, increased rapidly to peak at 10 15 days, remained stable 2 4 weeks and decreased thereafter, leaving an acellular fibrous scar 2 months post-transplantation (Figure 1A).

Direct recognition occurs when recipient Th lymphocytes recognize MHC-II antigens on intact APC in the allograft.

Using APC-T cell conjugates or TCR stimulatory surfaces, the overall effect of Nef was to reduce but not abrogate the TCR signal in the recipient T lymphocyte, resulting in a significant reduction of TCR induced tyrosine phosphorylation [13], [15].

Antibody-mediated AR occurs in a minority of transplant patients and is characterized by the recipient's B lymphocytes forming antibodies against donor antigens.