Sentence examples for recipient class from inspiring English sources

Donor CD8+ T cells are activated when their T-cell receptor (TCR) binds to recipient peptides presented in the context of recipient class I major histocompatibility complex (MHC) molecules (see Box 1 for a glossary of immunological terms).

HLA matching demonstrated a 2,1,1 mismatch, but there were no recipient class I or II HLA antibodies at the time of transplantation, and this proceeded with no complications.

This study indicated that the presence of recipient class I ligands for donor-activating and donor-inhibitory KIR genes would promote NK-cell functional recovery during NK-cell education, thus conferring some protection against leukaemic relapse in T-cell-repleted, haploidentical transplantation, which would be worthy of future study.

The interaction of recipients class I ligands and donor-inhibitory KIR genes and activating KIR genes have important roles on the process of NK-cell education in vivo and the initiation of alloreactivity in NK cells post-haploidentical transplantation.

We have clearly demonstrated that trogocytosis is not limited to antigen presenting cells as all donor hematopoietic blood cells, including the CD34+ stem and progenitor cells, acquired recipient MHC Class I molecules.

The recipient had Class I panel reactive antibodies' (PRAs) titre of 97%, but T- and B-cell IgG flow cytometric crossmatch was negative.

In one study, it was demonstrated that the introduction of a single transgene of the recipient MHC-class I gene into mismatched donor bone marrow cells resulted in the donor cells being able to present as 'self' MHC in the recipient, thereby altering the reaction of NK cells and preventing rejection [34].

George was Emeritus Professor of English at Hamilton College, where he was the inaugural recipient of The Class of 1962 Outstanding Teaching Award.

The E Street Band is this class' recipient of the award of musical excellence.

Using a standard mouse model for hematopoietic stem cell engraftment we were able to demonstrate that >80% of the donor cells carried recipient surface MHC class I proteins suggesting a fusion event.

Specifically, both the molecular and haematologic relapse rates were increased in recipient lacking a class I ligand for donor-inhibitory KIR.