Sentence examples for receptors point from inspiring English sources
Recent X-ray structures of bacterial and invertebrate pentameric receptors point to a striking conservation of the structural features within the whole family, even between distant prokaryotic and eukaryotic members.
To enhance functional surface expression of GluClβ receptors, point mutants or chimeras with GluClα segments were made in regions of the receptor previously shown to affect Cys-loop receptor trafficking and expression levels (SI Figure S2).
The marked differences in the properties of the ErbB receptors point to the possibility that inhibitory mechanisms may not adhere to a one-size-fits-all paradigm; cells may employ different inhibitory mechanisms to negatively regulate the different ErbB family members.
In any case, the unexpected similarities between apparently unrelated neurotoxicants in their effects on ionotropic glutamate receptors points to future experiments on the potential for convergent underlying mechanisms and outcomes involving excitotoxicity.
The most important policy-relevant question is how LRT of air pollution affects the air quality at a specified receptor point or area.
Our results show that receptor point mutations can not only alter receptor behavior, as shown for activating/inactivating mutations, but also can have more subtle effects changing ligand mechanism of action.
The QRA is conducted as a backward calculation starting from a pre-defined acceptable risk level at the receptor point (defined as an annual infection risk of 10−4 for pathogens and by reference doses (RfD) for chemical hazards) and results in an estimate of the corresponding acceptable concentration levels of the given hazards in the effluent.
Estimates were computed at each receptor point by numerical calculations using CadnaA software (DataKustik, Greifenberg, Germany).
For exposure, addresses located within 30 m from a receptor point were assigned the concentration of the nearest point.
The individual P2X1 receptor point mutations K136E, R139M and K140L had no effect on suramin sensitivity (n = 3, Figure 4C).
On a more speculative note, studies with the Drosophila melanogaster EGF receptor point to the possibility that other negative modulators may exist in humans.
