Sentence examples for receptor to proinflammatory from inspiring English sources

Indeed, an emerging theme in the biology of RAGE links this receptor to proinflammatory mechanisms.

However, the time-dependent switch of PAR1 from an exacerbating proinflammatory receptor to a protective anti-inflammatory receptor needs to be investigated before clinical trials can be recommended.

The time-dependent switch of PAR1 from an exacerbating proinflammatory receptor to a protective anti-inflammatory receptor needs to be investigated in other experimental models before clinical trials can be recommended.

SAA has been shown to bind to the ALXR (FPRL1/LXA4R) receptor and to elicit proinflammatory activities.

This anti-inflammatory cytokine diminishes the expression of inflammatory mediators, inhibits antigen presentation, and induces expression of endogenous TNF- α inhibitors (soluble TNF receptors) to suppress the effects of proinflammatory cytokines in periprosthetic tissues [ 47, 58].

Toll-like receptor 2 (TLR2), an important pattern recognition receptor, activates proinflammatory pathways in response to various pathogens.

Here we show that it is the α2A-AR that is upregulated in KCs leading to enhanced receptor binding and proinflammatory cytokine release in sepsis.

> -wrap-foot> PolyspecIVIG IVIG contains a broad array of multiple IgG antibodies and represents an established treatment to suppress inflammation by blocking the interaction between the Fcγ receptor and proinflammatory ligands [ 65] while reducing antigen-specific T-cell proliferation without inducing apoptosis [ 66].

As a consequence of Cathepsin B treatment, stimulated ATG7-mediated autophagy aggravates lipotoxicity via induction of nod-like receptor 3 proinflammatory response in rat insulinoma cells (Li et al., 2013).

The novel KD risk loci contained genes that have been implicated in T cell receptor signaling, proinflammatory cytokine regulation, as well as antibody-mediated immune responses.

In the collagen-induced arthritis model, B cells expressing IL-7 receptor are proinflammatory [ 46].