Sentence examples for receptor plasticity from inspiring English sources
In the brain, the Homer protein family modulates excitatory signal transduction and receptor plasticity through interactions with other proteins in dendritic spines.
Consistent with this is the observation of decreased neurotransmitter receptor plasticity in senescent rats (Pedigo 1994).
In other words, taking the receptor plasticity into account when performing docking simulation means that amino acid residues, loops and turns, can move slightly in different directions, giving the ligand a better chance to accommodate itself in the receptors' binding site.
These results suggested that the TMS changes observed before treatment might be the expression of disruption of glutamatergic receptor plasticity-related processes, and that this neurophysiological behaviour might correlate with executive functions.
Further studies will be required to determine how the marked transition in striatal CSPG expression early in life, and the period of receptor expression plasticity within the caudate/putamen later in development are related.
A theoretical background of receptor structural plasticity in the form of the energy landscape has been recently illustrated by Deupi and Kobilka.
hPSC-derived cortical neural networks are excitatory, driven by activation of AMPA -and NMDA-type glutamate receptors, and can undergo NMDA-receptor-mediated plasticity.
In order to mimic the natural, in vitro and in vivo, behavior of ligands and receptors, their plasticity or flexibility should be treated in an explicit manner [ 6]: our receptor is a protein that is an inherently flexible system.
Furthermore, stem cell-derived networks support NMDA-receptor mediated plasticity, in the form of chemical LTP.
Thus, at present, the relationship between these 2 forms of muscarinic receptor-dependent plasticity is unclear.
To analyse the functional maturity of stem cell-derived neural networks further, we investigated whether these neurons and networks could support NMDA-receptor mediated plasticity.
