Sentence examples for receptor phenotype from inspiring English sources

A major challenge in prostate cancer (CaP) treatment is evident due to molecular-based transformations resulting in the loss of response to and/or expression of the androgen receptor phenotype.

This hypothesis does not quite fit with our data, however, since we observed that knockdown of presynaptic neurexin and postsynaptic neurexin had the same receptor phenotype.

With regard to T cell receptor phenotype, lung TRM cells are also heterogeneous with regard to Vβ usage, in both CD4 and CD8 populations.

The low NR2A and high NR2C transcriptome expression detected now implicates a recapitulation of an immature NMDA receptor phenotype after SE, as the NR2B and NR2C subunits are highly expressed in the developing hippocampus, and around the third postnatal weeks these two subunits are replaced by NR2A and NR2D [90].

Clinical responses were observed in three of nine (33.3%) patients with the triple-negative receptor phenotype (ER−, PgR−, and HER2−).

Multifocal tumours, of varying receptor phenotype were found in 4 patients and in addition different regions of large tumours also showed varying receptor contents.

Importantly, our data demonstrate that neurexin mutant glutamate receptor phenotypes, at least in embryos, are restricted to A-type receptors.

Table II compares host receptor phenotypes between children with fatal or uncomplicated malaria outcomes.

Although a large battery of co-inhibitory receptor phenotyping was performed, the low number of patients included precludes any robust conclusion, especially in regard to correlations with clinical outcomes.

Sortilin loss abolishes apoptosis in mouse retina during development [9], protects lesioned corticospinal neurons against cell death [9], aggravates Trk receptor phenotypes present in p75NTR deficient mice [18], and increases embryonic lethality and sympathetic neuropathy in TrkA−/− heterozygous mice [18].

Examining these features in the photoactivated deprotonated intermediate structure of rhodopsin, we found support for the proposition that this GPCR structure contains elements of both the activated and inactive receptor phenotypes, as the TM7−HX8 segment resembled an active-like conformation while the TM7−TM2 interaction was still intact, resembling an inactive-like state.