Your English writing platform
Discover LudwigExact(3)
Since the regulation of the urotensin II/urotensin II receptor offers a great potential for therapeutic strategies related to the treatment of cardiovascular diseases, the study of selective and potent antagonists for urotensin II receptor is more fascinating.
The research on ligands modulating the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), one subtype of glutamate ionotropic receptor, offers opportunities to modulate fast excitatory synaptic transmission, and to identify new potential therapeutic agents for a range of neurodisease, such as schizophrenia and epilepsy.
The use of an estrogen receptor offers the advantage of a rapid kinetic response, yet the artificial nature of the fusion protein may alter the target gene response compared to wt MYC.
Similar(57)
Drugs that target the EGF receptor offer promise for more effective treatment of pancreatic cancer [ 1].
Compounds that only show fluorescence when they are bound to the receptor offer low background fluorescence in the aqueous phase and thus a high signal to noise ratio.
Our recent discovery of the substituted cyclobutane Boc5, one of the first non-peptidic agonists at glucagon-like peptide-1 receptors, offers the potential of combining oral availability with full agonism capable of eliciting antidiabetic and antiobesity effects.
In the context of Ca2+-mediated synaptic plasticity, regulation of the AMPA-receptor offers a potentially interesting comparison.
The development of allosteric ligands of neurotransmitter receptors offers the opportunity to modify endogenous neural activity while maintaining the temporal and focal components of endogenous signaling.
Therefore, the recent development of a glucagon-like peptide-1 (GLP-1)–oestrogen conjugate, which targets oestrogen into cells expressing GLP-1 receptors, offers an opportunity for a cell-specific and enhanced beta cell protection by oestrogen.
Although none of these arguments provides sufficient evidence for structural kinship, existing structural data and a new pedigree of bacterial glutamate receptors offer strong support.
Shape-persistent receptors offer clear benefits like preorganization to enhance binding affinities and their small degree of conformational freedom allows for a high correlation between design and experimental outcomes.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com