Sentence examples for receptor occupancy from inspiring English sources
In this mechanism, receptor occupancy causes individual receptors within the cell membrane to aggregate spontaneously.
However, that could be evaluated by using receptor occupancy.
So-called receptor occupancy studies measure just that.
In vivo brain mGluR5 receptor occupancy following systemic (i.p).
Lassen's plot displayed robust linearity (Fig. 6e), demonstrating uniform receptor occupancy among brain regions, and the receptor occupancy of ciproxifan at this dose was stably estimated as ~75%%.
Receptor occupancy following each administration was calculated to investigate its relationship with clinical effect.
Data from a dopamine D3/D2 receptor occupancy study with [11C]--PHNO were used.
Receptor occupancy is also very important experimental descriptor for evaluating target engagement by the examined drug.
These doses were chosen based on previous studies of receptor occupancy by flumazenil in rats [15].
We also demonstrated the in vivo 5-HT2A receptoccupancyncy of olanzapine using positron emission tomography.
