Sentence examples for receptor it from inspiring English sources

Given the assumption that shape complementarity is a prerequisite for binding between a ligand and its receptor, it follows that active molecules with similar shapes could be active against the same targets.

Interestingly, when TNFα binds to its receptor it results in inhibition of bone mineralisation.

When adiponectin attaches to its receptor it activates AMP kinase [ 19, 67], promoting so glucose uptake by muscles via intracellular translocation of the GLUT4 transporters.

When IGF-1 binds to its receptor, it activates the tyrosine kinase activity of the receptor leading to phosphorylation of tyrosine residues on the receptor and IRS proteins.

If it comes up with a dud receptor, it dies during its training.

HA is one of the principal ECM molecules and together with its CD44 cell surface receptor, it is implicated in cancer cell invasion and metastasis [ 62].

Despite darbepoetin alfa's reduced affinity for the erythropoietin receptor, it has increased potency due to its extended serum residence time (Egrie et al, 1997).

"No one had ever found out which receptor it was working on".

When he made these 7 changes to the ancestral receptor, it behaved just like a new glucocorticoid receptor.

When the proper growth factor binds to this receptor, it sets off a series of reactions that spur cell growth and retard cell death.

When drug action is elicited by a specific target receptor, it is important to kinetically clarify the relationship between them.