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With olfactory receptor input, RANCs recognize patterns of signals to discriminate odors.
We then tested whether uniform activation of PI3K, without any receptor input, causes cell polarization (Fig. 1C, left).
Experiments in brain slices have demonstrated that the activation of GABA release from interneurons can depend on NMDA receptor input [15], [16].
Nevertheless, single-unit recordings from awake monkeys reveal cutaneous inputs to MI that appear to segregate in modality-specific maps, with neighboring representations being differentially responsive to cutaneous and joint receptor input [25].
With incomplete blockade of the receptor input layer, proliferative and survival signals can be generated from several different dimer pairs.
In particular, the biological "olfactory space" can be derived from the data, that is, a description of how similar and dissimilar different odors are at the level of primary receptor input.
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There is a stereotyped map of odorant receptor inputs in the olfactory bulb [62], but the concept of magnification requires two such maps.
Recent work from several laboratories indicates that the coordination of endothelial cell adhesion events with growth factor receptor inputs regulates endothelial cell responses during angiogenesis.
Central processing of oscillatory receptor inputs could contribute to distinguishing self-generated stimuli from external stimuli while maximizing sensitivity to external stimuli.
How higher-order neural circuits respond to stimuli from these receptor inputs to coordinate the change from pre- to postcopulatory states in females is unknown.
Perhaps most critically, chlorpyrifos-exposed males showed hyperreactivity of hepatic adenylyl cyclase to stimulation of β-adrenoceptors or glucagon receptors, inputs that are responsible for promoting gluconeogenesis and the consequent rise in circulating glucose levels.
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