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It can be noted that the putative flatworm peptide receptor count greatly outnumbers the set of currently known peptide ligands.
This reported sequence count is not equivalent to a receptor count, as many of these sequences may represent fragments of a single protein or prove to be redundant sequences.
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Some markers, such as cell and receptor counts can never be negative.
CFU-M = colony forming units-macrophage; CTR = calcitonin receptor; counts per minute (cpm); PBS = phosphate-buffered saline; TJR = total joint replacement; TRAP = tartrate resistant acid phosphatase.
This is in large contrast with the membrane proteome of E. coli where receptors count for only 5% of the membrane proteome, leaving transporters as the most prominent group with 40%, compared with 15% in humans and 32% in S. cerevisiae's membrane proteomes [ 5, 6].
It was observed that the rearranged T-cell receptor β count correlated well with total lymphocyte counts from both study populations (Baltimore R = 0.602, Uganda R = 0.497; p < 0.001) and the ability for this measurement to determine antiretroviral initiation was similar to total lymphocyte counts, which can be used to determine eligibility in HIV + children.
The third term in Eq (13) arises because the diffusive flux of transcription factor molecules to the binding site fluctuates at low input concentration c; in effect the receptor site "counts" the number of molecules arriving into its vicinity during a time window, and this number is of the order ∼Dacτg.
In the amygdala, in the presence of 2 nM and 20 nM 3H-CCK-8 ligand, the CCK receptor binding counts were 15.8 fmoles/mg and 49.3 fmoles/mg in control mice, and 56.8 fmoles and 142.9 fmoles/mg in tg mice, respectively (Fig. 1F), revealing a 2.9 3.6-fold 2.9 3.6-foldetween control andifference
In the hippocampus, in the presence of 2 nM and 20 nM 3H-CCK-8 ligand, the CCK receptor binding counts were 22.2 fmoles/mg and 67.4 fmoles/mg in control mice, and 114.8 fmoles and 301.3 fmoles/mg in tg mice, respectively (Fig. 1E), revealing a 4.5 5.2-fold 4.5 5.2-foldetween control andifference
To estimate the transmission rate of an mRNA transcript from donor to receptor, we counted the numbers of the donor and receptor RNA-Seq reads, respectively, which perfectly matched the donor genome within the transmission window (Additional file 1: Figure S3), and the raw counts were then normalized to RPM (read per million).
([H]-thymidine and steroid receptors were counted for Group 4).
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