The receptor copy number is 200 400 and it is concentrated in the flagellar pocket (Vanhollebeke et al., 2008).
The optical transparency of the glass allowed for further analysis in the form of fluorescence in situ hybridization (FISH) to determine androgen receptor copy number in LNCaP cells.
Assuming that the receptors are predominantly localised at the flagellar pocket, and using the known receptor copy number and VSG diffusion rates, we have calculated that each receptor should contact another receptor approximately once each second.
Scanning electron microscopy (SEM) is utilized to assist searching the underlying reasons for the observed difference in CD4 receptor copy number per cell determined by MRM MS and CD4 expression measured previously by flow cytometry.
Epidermal growth factor receptor copy number and EGFR mutation may be related, as out of five EGFR mutant samples, two samples showed high polysomy and one sample showed EGFR amplification.
Separating signal from noise, or finding rare cells expressing low-abundance antigens in such experiments may be difficult when a signal to background ratio of less than 10 is observed in cells expressing moderate receptor copy numbers as seen in these experiments.
This study was designed to explore the relationship between epidermal growth factor receptor (EGFR) copy number and EGFR protein expression in oral cavity squamous cell carcinoma (OSCCs) in Taiwan.
BC: Breast cancer; ER: Estrogen-receptor; PR: Progesterone receptor; CNAs: Copy Number Aberrations; MAD: Median Absolute Deviation SAMM: Significance Analysis of Microarrays; ACGH: Array-based comparative genomic hybridisation; CBS: Circular binary segmentation; BAC: Bacterial Artificial Chromosome; AMP: Amplification.
The abbreviations used are: EOC: epithelial ovarian cancer; PPARg: peroxisome proliferator-activated receptorγ; VDR: vitamin D receptor; CNA: copy number alteration; H&E: hematoxylin and eosin; CCNE2: cyclin E2; CGH: Comparative Genomic Hybridization.
Comparative frequency of Fc gamma receptor 3B (FcopyB) copy number (CN) variants in rheumatoid arthritis patients positive and negative for rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) autoantibodies.
In order to determine whether the Man-6-P/IGF-II receptor gene copy number is altered in breast cancer we analysed specimens of invasive breast carcinoma from 51 patients by Southern blotting.
