Sentence examples for receptor capability from inspiring English sources

Hence, the S259V mutation is expected to impair the receptor capability to effectively bind PTC and to be activated, in an indirect fashion.

The tri-modal contrast imaging functionality together with molecular receptor targeting capability and biocompatibility makes MF-nHAp a promising biomineral contrast agent for combinatorial molecular imaging.

Analysis of modified EGF receptor dimerization capability was performed using SDS-PAGE with Coomassie blue staining, exactly as described [21], [22], [23].

Full agonism refers to the ability of an agonist ligand to produce the full maximal receptor response capability of the target tissue or system.

Thus, both modified chemokines and small derivative molecules maintaining the HIV-inhibitory function, but devoid of receptor-activating capability, have been generated.

A novel series of molecules were designed with multiple sex-steroid receptor modulating capabilities by coalescing the pharmacophores of known anti-CaP molecules that act via modulation of ER and/or AR, viz.

This is because many similar aromatic, lipophilic compounds have been shown to have endocrine receptor binding capabilities [ 34, 35].

These findings illustrate that the TRAIL receptors have varying, cell type-specific and in parts receptor specific capabilities to recruit different signalling complexes to their intracellular domain.

Natural compounds are considered to have a large degree of "drug likeness" because it has been suggested that most of them have some receptor-binding capability [ 3].

In rats, prenatal exposure to the OC pesticides dieldrin and lindane reduces GABAA receptor binding capabilities in the brainstem (Brannen et al. 1998).

Cardiac receptor binding capabilities were determined by methods described previously (McMillian et al. 1983; Slotkin et al. 1987a; Song et al. 1997; Zahalka et al. 1993).