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A polymerizable anion receptor based on a boric acid ester was synthesized.
The sequential virtual screening workflow based on ligand and receptor based query was followed to identify novel PKCβII inhibitors.
In 1991, Ishihara and colleagues isolated the rat secretin receptor based on a direct expression cloning strategy.
It is therefore likely that the models are unable to reliably extrapolate for this receptor based on the H1 receptor.
A novel artificial anion receptor based on phenylhydrazone structure was designed, synthesized and characterized.
Receptor based MFA model showed better results when compared with least squares and pharmacophore based models.
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In the most basal insects no evidence for any part of the olfactory receptor-based system was found.
These properties establish the potential for using GPCR SMALP in receptor-based drug discovery assays.
Results generated from the ligand-based model were found to be superior to those obtained by the receptor-based model.
Receptor-based in vitro data could be retrieved for all the 12 substances.
In this way, ligand information can be transferred to receptor-based modelling.
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