Sentence examples similar to receptor a knock from inspiring English sources

Therefore, we evaluated survival of IL-17 receptor A knock-out (IL-17RA−/−) mice given a pulmonary infection with C. neoformans strain H99γ.

Furthermore, NMDA activation has been recently reported to induce repressive transcription via extrasynaptic NMDA receptors in YAC128 mice, a knock in mouse model for HD (Okamoto et al, 2009).

To test this hypothesis we have used an Interleukin-1 receptor antagonist knock out mouse model of RA on a Balb/c background (Balb/c IL1ra-/), which spontaneously develops inflammatory arthropathy with inflammatory cellular infiltration, pannus formation and periarticular bone erosions, similar to RA in humans, with 100% penetrance by weeks 20 of age [ 10].

We and others have demonstrated previously that ghrelin receptor (GhrR) knock out (KO) mice fed a high fat diet (HFD) have increased insulin sensitivity and metabolic flexibility relative to WT littermates.

We utilized a G-CSF receptor knock out (GCSFR−/−) mouse model (on a C57BL/6 genetic background) to study the effects of myelopoiesis in PC.

Nevertheless, we previously showed that germline CSF-1 receptor (Csf1r) knock out (KO) or Csf1 mutation is associated with an absence of mature PC, reduced crypt proliferation and lowered stem cell gene, Lgr5 expression.

More convincingly, atherosclerosis prone male apolipoprotein E (apoE) deficient mice that also lack the AT1A receptor (double knock out) exhibit reduced atherosclerosis compared with wild type apoE KO mice [ 15].

While it is not clear what, in this case, causes direct additional cellular depolarization creating the resonant frequency shift, it was shown that in 5HT1A KO mice (i.e. serotonin receptor knock-outs, a model for increased anxiety), that there was an increased theta power increases over wild type [18].

Remarkably, prepro peptide and double (OX1R/OX2R) receptor knock out (KO) mice reproduce a sleep phenotype known in humans and dogs as narcolepsy/cataplexy.

This result prompted us to investigate CB1 dependent regulation of neurogenesis utilizing CB1 receptor knock out animals as well as the CB1 receptor antagonist AM251 in Nestin-GFP-reporter mice.

To study type 2 diabetes in a mouse model we chose the leptin receptor knock out mouse model (Leprdb).