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More recently, sophisticated electronic alarms, some of which incorporate radio beacons, and more tamper-resistant wiring and electronic locks have been produced.
More recently, sophisticated algorithms have been developed to better quantify complex histologic patterns on whole slide images (i.e. the analyses are no longer limited to small TMAs), including the spatial heterogeneity of different cell types (e.g. stromal, lymphocyte, and tumor) in the cancer and its environment8,9,10.
Recently, sophisticated methods have been proposed, such as neural networks and autoregressive average models [44, 45].
Recently, sophisticated methodologies for the development of EST-PCR markers for plants have been reported [ 22- 25].
First, until recently, sophisticated methods that are costly, labor intensive, and not always routinely available were required for identification of most MSAs, limiting their widespread use.
More recently, sophisticated lineage conversion approaches have allowed for the direct generation of neurons and neural cell types from adult cells by means of overexpressing key transcription factors (for a detailed description see Tsunemoto et al, 2015).
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Only recently have sophisticated technologies allowed researchers to begin bridging the gap between the consulting room and the laboratory.
The algorithms required to identify the variants contributing to disease risk have only more recently become sophisticated enough.
More recently, more sophisticated targeted treatments are being used to treat cancer that has spread beyond the breast.
Recently, more sophisticated analyses of environmental behavior and the behavior of building users have been developed and implemented.
But recently, more sophisticated, upscale restaurants have been popping up, taking the Caribbean and Latin American fare in the area to a new culinary level.
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