Details of the recently elucidated biosynthetic pathways of caffeine and related purine alkaloids are reviewed.
Integrated structural biology recently elucidated the architecture of Mediator and its position on RNA polymerase II.
The recently elucidated crystal structures of this enzyme provide an opportunity for the discovery of inhibitors through rational drug design.
The recently elucidated MRB1 architecture will be instrumental in putting functional data from individual subunits into context.
This paper provides an overview of glucansucrase enzymes, their recently elucidated crystal structures, their reaction and product specificity, and the structural analysis and applications of α-glucan polymers.
We have predicted a viable signalling pathway characterized in terms of the genes responsible that may be the PfPKB pathway recently elucidated in Plasmodium falciparum.
The recently elucidated methylerythritol phosphate (MEP) pathway for isoprenoid biosynthesis is essential in eubacteria (including Escherichia coli), the malaria parasite, and plants, but is absent in animals.
The structural and functional mechanism by which ABA is perceived by these receptors and consequently leads to inhibition of the PP2Cs has been recently elucidated.
In this chapter, we will review the recently elucidated CCOs and mechanisms of tumor initiation in the most common forms of cancer; cutaneous basal and squamous cell carcinoma.
The thermodynamic (enthalpy and free-energy) barriers to water and solute entrance into nanopores located at membrane surfaces have been recently elucidated by means of specialized non-equilibrium simulations protocols.
Using both existing and newly developed tools to analyze transmembrane segments of all available membrane protein three-dimensional structures, including that very recently elucidated for the GPCR, rhodopsin, we report here the finding of frequent non-α-helical components, i.e. 310-helices ("tight turns"), π-helices ("wide turns") and intrahelical kinks (often due to residues other than proline).
