Sentence examples for recent trials are from inspiring English sources
Two recent trials are relevant for deciding between these hypotheses.
Thus, criteria defining 'active disease' have become more lenient, yet the ranges of baseline joint counts and disease activity in subjects enrolled in most recent trials are still remarkably similar.
The only recent trials are the mega-trial from India showing no effect 2 and a placebo-controlled trial of VAS administered with vaccines in Guinea-Bissau also showing no overall but sex-differential effects (unpublished data).
A currently unsolved issue in secondary prevention of vascular disease is whether the beneficial effects of additional, aggressive lipid lowering as observed in recent trials are the result of a reduction in inflammatory and oxidative stress or that of a greater lipid lowering effect per se.
Although the protective effects of circumcision were slightly less than those found in the Orange Farm trial, the results of these more recent trials are clearly consistent with the South African trial, making the case for a protective effect of MC very strong.
This is potentially an important variable because the time span for our study covers two decades and it is possible that more recent trials were more likely to conform to the conduct outlined in reporting standards such as CONSORT, which were first published in 1996 and revised in 2001 [22].
Several explanations for the trends in the findings of recent trials were discussed.
This policy has been widely adopted and now assures that the existence of most recent trials is known [ 29].
This is an important point given the fact that the patients included in the recent trials were a relatively younger group of patients.
It is likely that the inconsistency between the meta-analysis and the recent trials is, at least partially, due to publication bias and differences in target population.
Similarly, more recent trials were more likely to justify their sample sizes and comment upon the power of their studies than earlier ones.
