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A recent trial indicated that taking 500 mg/day vitamin C for 2 months reduced serum uric acid by 0.5 mg/dl [ 62].
When treatment is needed, UK practice has been to use chlorambucil; however, a recent trial indicated that better and more durable disease responses can be achieved using fludarabine and cyclophosphamide, in combination.
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A very recent trial indicates that T3 replacement in patients with heart failure has beneficial contractile effects [ 59].
Indeed, more recent trials indicate similar complication rates between pregnant and non-pregnant patients [ 20, 21].
Recent trials indicate that agents blocking the RAAS might be more effective for this purpose through diverse pleiotropic effects.
However, the results of some recent trials indicate that there is no guarantee that the assumption will hold.
However, more recent trials indicate that other FUN regimens may be less toxic (Lombardi et al, 2000; Zambetti et al, 2000).
This is of particular interest in the light of the results of recent trials, indicating that sequential treatment during the disease-free period may improve OS in breast cancer (Coombes et al, 2007; Kaufmann et al, 2007).
Recent trials indicate that 5-year survival rate has reached a plateau, with little or no improvement by conventional treatment modalities (Link et al, 1986; Bacci et al, 2001; Bielack et al, 2002).
Some early data suggested that the monoclonal antibody, bevacizumab, may be associated with increased risk for VTE (Shah et al, 2005); some recent trials indicate that bevacizumab in the context of contemporary chemotherapy regimens is not associated with significant elevations in risk (Hurwitz et al, 2004).
20 A recent clinical trial indicated reduced OA knee pain after treatment with strontium ranelate, an effect that may be mediated through reduced bone turnover.
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CEO of Professional Science Editing for Scientists @ prosciediting.com