These factors included: referral to a previous phase I study, recent trial start date, private sponsorship, single-agent treatment, and multicentre organisation.
In recent months, as the start date of the new cap-and-trade program neared, California regulators have fine-tuned the rules, industry by industry, to avoid imposing severe economic hardship while trying to keep the rules stringent.
Others have scoured the program's Web site or Twitter feed, @CitibikeNYC, which has supplied evolving answers to New Yorkers about the start date in recent weeks.
The length of this period is flexible: start date depends on recent culture results, patient care settings, and clinical assessment; end date is determined by 2 negative cultures, which are submitted weekly posttherapy.
If the start date of a more recent partnership preceded the end date of an earlier partnership, the partnerships were defined as concurrent, and the duration of overlap was defined as the difference between these two dates.
We collected basic information of selected simulators, including short and long descriptions, URL to package web page, project start date and version and release date of the most recent release.
After advertising a July start date since the spring, the city had begun to hedge in recent days.
Exposure to drugs was collected before the start date and categorized as follows: current use, when the supply of the most recent prescription lasted until the start date or ended in the 90 days before the start date; recent use, when supply of the most recent prescription ended more than 90 days before the start date; and non-use, when there was no recorded use any time before the start date.
Because patients could switch between drugs, the time from start date of first drug does not always reflect time since starting the most recent drug.
The median start date was in 2006 (range 1997 2011); when studies evaluating discussion forums were excluded, the start date was more recent (median 2008, range 2000 2011).
