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AT III levels are known to decrease after recent or active thrombosis, surgical procedures, disseminated intravascular coagulation, or full-dose heparin administration.
However, there is limited literature available on the practical approaches to conducting such assessments in areas of recent or active conflict [ 12, 18– 23].
Titres ≥ 1 400 were considered to be high-positive titres, and were interpreted as indicating either recent or active infection [ 18].
In this study, we also applied the diagnostic algorithm described by Riffelmann that anti-PT IgG ≥100 IU/mL as diagnostic of recent or active infection with B.pertussis.
These patients had no evidence of recent or active blood loss, no history of hematologic disease or chronic renal failure, and no need for renal replacement therapy.
Recent or active treatment with anti-neoplastic therapy is a common exclusion criterion (Fearon et al, 2006); however, this has the pitfall of including patients with progressive or refractory disease.
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A recent meta-analysis showed that PPIs at "standard" doses (compared with no treatment, placebo, or an H2 receptor antagonist) administered beforehand facilitated EGD by reducing the proportion of patients with stigmata of recent hemorrhage or active bleeding and by reducing requirement for endoscopic therapy [42].
A recent meta-analysis showed that PPIs at "standard" doses (compared with no treatment, placebo, or an H2 receptor antagonist) administered beforehand facilitated EGD by reducing the proportion of patients with stigmata of recent hemorrhage or active bleeding and by reducing requirement for endoscopic therapy [ 42].
It has been suggested that IGRAs based on a prolonged period of incubation with mycobacterial antigens could detect response of central memory T-cells [24] and are more sensitive to identify past latent TB infection; on the other hand, short-incubation IGRAs mainly detect circulating effector memory T cells whose numbers correlate with recent or ongoing active M. tuberculosis infection [33].
High risk for bleeding was arbitrarily defined as a platelet count of less than 40 × 10/L, an activated partial thromboplastin time (aPTT) of more than 60 seconds, a prothrombin time of more than 2.0 international normalized ratio, recent major bleeding, or active bleeding.
High risk for bleeding was arbitrarily defined as a platelet count of less than 40 × 10/L, an activated partial thromboplastin time (aPTT) of more than 60 s, a prothrombin time of more than 2.0 international normalized ratio, a recent major bleeding, or active bleeding.
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