Sentence examples for recent implications from inspiring English sources

One of them is kynurenine aminotransferase, leading to the production of kynurenic acid (KYNA), a broad-spectrum endogenous antagonist of excitatory amino acid receptors [ 12, 13] with emerging recent implications in immunomodulation [ 14, 15].

The later observation is consistent with the recent implication on the function of YhjD protein in LPS transport [11], [12].

The recent implication of T (brachyury) gene duplication in familial chordoma [10] and T copy number gain in sporadic chordoma [11] prompted us to search for a possible association in our group of sporadic chordomas.

The recent implication of cohesin in regulating chromosome conformation [20], [27], [36], [44] together with its detection in ESC identity RNAi screens [32], [33] prompted us to investigate the role of RAD21 in ESCs in more detail.

The recent implication of PPB2 and its downstream target cofillin in Aβ-induced loss of dendritic spines [4] suggests that this molecule may serve as a mechanistic link between Homer1b cluster dispersal and dendritic spine loss [4], [12].

Further evidence from SNP-based genome-wide association studies has been equally unremarkable (less than 2-fold difference), including the recent implication of two SNPs (rs401681 and rs2736098) consistently but weakly associated with a variety of human malignancies [30], as well as other SNP genotypes detected in genome-wide association studies of glioma [54], [55].

To do so will require expanding the mechanistic insight based on the recent implication of chromatin remodelers in Type II EC using more potent and specific tool compounds.

In the light of the recent implication of actin in early stages of endocytosis, we investigated the role of PI3K in the clathrin-dependent (Tf) and -independent entry (IL-2R).

Given the recent implication of synaptic genes in ASD susceptibility (Durand et al. 2008; Zoghbi 2003) and the strong functional candidacy of CADM2, its involvement in ASD warrants further investigation.

Similarly, the well described role of auxins in establishment of embryo polarity [ 41] or the recent implication of brassinosteroids in the acquisition of embryonic competence [ 42] was confirmed in citrus embryos by expression of citrus orthologs of genes related to signalling and biosynthesis of these hormones [see Additional files 6, 7, and 8].

Moreover, the strong upregulation of Hes1 that we detect in vivo and in cerebellar stem cells is consistent with it being a Notch and Gli target (Ingram et al, 2008; V Wallace, personal communication) and is interesting in view of its recent implication in the prevention of senescence (Sang et al, 2008).