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All-cause mortality was lower among those receiving novel antithrombotic agents.
The renal complete response rate for patients with CrCl<40 ml/min at diagnosis receiving novel agent induction therapy compared to those not receiving novel agent induction therapy was 40 vs 16% (P<0.001).
The complete renal response rate for patients with RI at diagnosis receiving novel agent induction therapy compared to the rest was 40 vs 16% (P<0.001).
Patients treated with novel agent combined chemotherapy especially did not show superior survival rates to conventional chemotherapy in spite of higher ORR in patients receiving novel agents.
In the absence of large randomized studies, institutional case series can provide useful insights into the efficacy, toxicity and management of patients receiving novel agents.
The median overall survival (OS) for patients with RI at diagnosis receiving and not receiving novel agent induction therapy was not reached vs 46 months (P<0.001).
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This informativity measure is equivalent to the mispricing measure used above and here quantifies mispricing from the viewpoint of a trader who received novel information, and determines the expected profit that can be gathered based on the information advantage.
In this study, all of the 27 patients having EMD involvement at diagnosis received novel agents-containing therapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com