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Subjects received study medication for 18 h a day.
Safety was evaluated in patients who received study treatment.
Thirty-four evaluable subjects were enrolled and received study drug.
RESULTS: Twelve patients were enrolled and received study drug.
All participants received study information and signed an informed consent.
The majority of patients (91.0%) received study treatment as outpatients.
RESULTS: Sixty patients received study drug and were included in the safety and efficacy analyses.
RESULTS: Thirty-one patients were enrolled onto the study, and 30 patients received study treatment.
Any patient who prematurely withdrew after having received study medication was encouraged to undergo Visit 3.
Safety analyses were performed on the "safety" population (randomised patients who received study medication).
Patients received study formulations during ICU stay for a maximum of 28 days.
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