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A significantly higher cholangitis rate was seen in patients who received EST plus mechanical lithotripsy, compared to those treated with EPLBD (13.3% versus 0.0, P = 0.026).
However, with removal of large stones (more than 15 mm), the requirement of ML was less than that for patients that received EPLBD compared to those that received EST.
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7,635 contigs (22%) received ESTs from all life cycle stages, and these universally expressed genes represented a majority (a mean of 74.5%) of the ESTs from each life cycle stage.
In the RCT comparing EPLBD with EST plus ML, cholangitis rate was higher in the patients receiving EST plus mechanical lithotripsy compared to EPLBD (13.3% versus 0.0, P = 0.026).
However, among sensitivity analyses, patients receiving active EST (33%) were assumed to experience disease stabilisation for 6 months based on dacarbazine (DAC) results [ 17].
A significant percentage of ESTs received no hits at all: 41% and 48% for S. pratensis and C. orbicularis, respectively.
Requests received after 2 00 p.m. EST are subject to being processed the following business day.
All supporting documents (e.g., transcripts and reference letters not submitted online) must be received by 5 00 p.m. EST on the stated deadline date.
So far, only the partially and totally intronic transcripts (PINs and TINs), which constitute more than half of the clusters of unspliced ESTs, have received attention in systematic studies [ 24– 26].
Recently, EST-SSRs have received much attention as the increasing amounts of ESTs being deposited in databases for various plants [ 17- 19].
An Alfred P. Sloan Foundation commission through EST, it first received productions at Cleveland Playhouse and Geva Theatre Center.
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