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Conversely, thymocytes that express TCR with low affinity for self peptide-MHC molecules receive survival signals, initiate positive selection of the cells and give rise to mature CD4 or CD8 T cells [5], [6].
Such benefits might include establishment of a work force that will be present already when the subordinate inherits the dominant breeding position [11] [13], being allowed to stay in the group ('pay-to-stay') and receive survival benefits [8], [14] [19], or access to breeding resources for the subordinate's own reproduction [20], [21].
These receptors also assist retaining B-cells in the SLOs that is essential for B-cells to receive survival cues and become activated in the presence of antigen.
Centrocytes with high affinity B cell receptors are more likely to successfully bind antigen and receive survival signals, while centrocytes with low affinity receptors fail to bind and undergo apoptosis.
Those GC B cells that can engage Tfh cells will receive survival and differentiation cues to exit the GC as long-lived plasma cells or memory cells or to undergo further rounds of somatic hypermutation.
Conceivably, CLL cell-derived CCL3 may attract these cells, creating a favorable microenvironment which allows CLL cells to interact with T cells and NLC to receive survival and proliferation signals.
Similar(53)
There is a case that received survival benefits from conversion surgery following chemotherapy after diagnostic metastasectomy in pancreatic cancer with synchronous liver metastasis.
The present case received survival benefits from conversion surgery following chemotherapy after diagnostic metastasectomy for pancreatic cancer with synchronous liver metastasis.
They also received survival training and preparation for other technical aspects of the mission.
Mice received survival surgeries when tumors reached approximately 490 mm3 (± 95).
Similarly, of the six ewes which showed partial restoration of ovarian function, only three had received survival factors and only two had received post-operative aspirin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com