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Modified Poisson regression was used to predict receipt of lines of treatment.
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For transfected variants, frozen batches of stock generated shortly after receipt of cell lines from the repositories were used.
Interestingly, receipt of subsequent lines of treatment was significantly affected by SEER-registry area.
Additional demographic and clinical characteristics of mCC Medicare beneficiaries by receipt of treatment lines are described in Table 1.
This study uses the SEER dataset linked with Medicare (SEER-Medicare) claims to examine factors associated with receipt of subsequent lines of chemotherapy or biologics.
ACE-27 comorbidity score was not significantly associated with receipt of first-line bevacizumab.
No significant association was seen between health system type and receipt of first-line bevacizumab, and none of the other associations were substantially altered.
Surgery of the primary site and being married were associated with receipt of second-line treatment (RR: 2.05, P < 0.0001 and RR: 1.46, P < 0.0001, respectively).
Attempts have been made to identify poor mobilisers prospectively, to justify their receipt of first-line plerixafor rather than conventional chemotherapy mobilisation.
Among elderly mCC patients, the receipt of second-line treatment depends on the chemotherapy drugs/biologics received in the initial treatment.
In an article by Wang et al, the authors used a cohort of patients aged 65 years and older to assess receipt of first-line recommended treatment according to National Comprehensive Cancer Network guidelines.
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