Sentence examples for recapitulating important from inspiring English sources

NTZ might represent a new class of small molecules capable of potentiating and recapitulating important antiviral effects of IFN.

However, it also has well-recognized limitations in terms of recapitulating important features of the human disease and downstream clinical predictability46.

Notwithstanding these incongruencies, studies on endothelial cells strengthen, on one side, the role of mTOR in glycotoxicity, and underscore, on the other side, the potential of the Phoenix cell model in recapitulating important biochemical aspects of nutrient-related human pathology.

Natural and experimental helicobacter infections in mice reproducibly recapitulate important features of human disease.

With new advances in tissue culture and engineering, these model systems are able to provide increasingly accurate, high-throughput and cost-effective models that recapitulate important characteristics of cell and tissue growth in vivo.

Together, these findings indicate that this 3D PCa PDX model recapitulates important pathological properties of PCa bone metastasis, and validate the use of this model for controlled and systematic interrogation of complex in vivo tumor-stromal interactions.

These results demonstrate that murine CML recapitulates important features of human CML.

The first step to achieve this would be to develop an animal model that more accurately recapitulates important aspects of clinical ZIKV disease as observed in humans.

To conclude, our primate model data reveal that SHIV-E1p5 recapitulates important aspects of HIV transmission and pathobiology in humans.IMPORTANCE Understanding the protective principles that lead to a safe, effective vaccine against HIV in nonhuman primate (NHP) models requires test viruses that allow the evaluation of anti-HIV envelope responses.

The 3D cultures allow us to propagate cells in a system that recapitulates important aspects of the plasticity and heterogeneity of the tumor.

Cancer metastasis models driven by the introduction of oncogenic mutations in a tissue-specific manner can faithfully recapitulate important aspects of tumor metastasis.